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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
46.67
Human Site:
T277
Identified Species:
73.33
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
T277
T
A
E
N
R
K
K
T
M
D
K
I
I
R
G
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
T277
T
A
E
N
R
K
K
T
M
D
K
I
I
K
G
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
T304
T
A
E
N
R
K
K
T
M
D
K
I
I
K
G
Dog
Lupus familis
XP_851971
482
53401
T275
T
A
E
N
R
K
K
T
M
D
K
I
I
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
T277
T
A
E
N
R
K
K
T
M
D
K
I
I
K
G
Rat
Rattus norvegicus
P67999
525
59113
T301
T
G
E
N
R
K
K
T
I
D
K
I
L
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
T258
T
G
E
N
R
K
K
T
I
D
K
I
L
K
C
Chicken
Gallus gallus
P18652
752
84421
T288
Q
G
K
D
R
K
E
T
M
T
L
I
L
K
A
Frog
Xenopus laevis
P10665
733
82620
T270
Q
G
K
D
R
K
E
T
M
T
L
I
L
K
A
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
T275
Q
G
K
D
R
N
E
T
M
N
M
I
L
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
G472
S
P
F
A
T
S
D
G
Q
V
Q
Q
S
E
I
Honey Bee
Apis mellifera
XP_395876
456
51514
T279
T
S
D
N
R
K
K
T
I
E
K
I
L
R
G
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
T312
Q
G
R
D
R
N
D
T
M
T
Q
I
L
K
A
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
T282
T
A
E
N
R
K
K
T
I
E
K
I
L
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
I269
R
D
L
K
P
E
N
I
L
M
D
V
D
G
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
66.6
N.A.
66.6
33.3
33.3
26.6
N.A.
0
66.6
26.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
86.6
66.6
66.6
66.6
N.A.
13.3
100
53.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
7
0
0
0
0
0
0
0
0
0
0
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% C
% Asp:
0
7
7
27
0
0
14
0
0
47
7
0
7
0
0
% D
% Glu:
0
0
54
0
0
7
20
0
0
14
0
0
0
7
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
40
0
0
0
0
0
7
0
0
0
0
0
7
47
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
7
27
0
0
87
34
0
7
% I
% Lys:
0
0
20
7
0
74
60
0
0
0
60
0
0
74
0
% K
% Leu:
0
0
7
0
0
0
0
0
7
0
14
0
54
0
0
% L
% Met:
0
0
0
0
0
0
0
0
60
7
7
0
0
0
0
% M
% Asn:
0
0
0
60
0
14
7
0
0
7
0
0
0
0
0
% N
% Pro:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
27
0
0
0
0
0
0
0
7
0
14
7
0
0
0
% Q
% Arg:
7
0
7
0
87
0
0
0
0
0
0
0
0
14
0
% R
% Ser:
7
7
0
0
0
7
0
0
0
0
0
0
7
0
0
% S
% Thr:
60
0
0
0
7
0
0
87
0
20
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _